2.56 real mastermix probe Search Results


protoscript ii first strand cdna synthesis kit  (New England Biolabs)
99
New England Biolabs protoscript ii first strand cdna synthesis kit
Protoscript Ii First Strand Cdna Synthesis Kit, supplied by New England Biolabs, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/ProtoScript+II+First+Strand+cDNA+Synthesis+Kit/ppr0633349-122-7-14
Average 99 stars, based on 1 article reviews
protoscript ii first strand cdna synthesis kit - by Bioz Stars, 2026-11
99/100 stars
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2.56 real mastermix probe  (5 PRIME)
90
5 PRIME 2.56 real mastermix probe
2.56 Real Mastermix Probe, supplied by 5 PRIME, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/5+prime+mastermix/pm22870235-90-19-21
Average 90 stars, based on 1 article reviews
2.56 real mastermix probe - by Bioz Stars, 2026-11
90/100 stars
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dedicated ultrasound probe  (ICONEUS)
94
ICONEUS dedicated ultrasound probe
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
Dedicated Ultrasound Probe, supplied by ICONEUS, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/IcoPrime-4D/bio_rxiv__64898__2026__05__13__725039-67-36-39
Average 94 stars, based on 1 article reviews
dedicated ultrasound probe - by Bioz Stars, 2026-11
94/100 stars
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infinium probes  (INFINIUM Inc)
90
INFINIUM Inc infinium probes
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
Infinium Probes, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/infinium+i+probes/pmc03855576-99-17-18
Average 90 stars, based on 1 article reviews
infinium probes - by Bioz Stars, 2026-11
90/100 stars
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256 hiscript ii 1st strand cdna synthesis kit  (Vazyme Biotech Co)
99
Vazyme Biotech Co 256 hiscript ii 1st strand cdna synthesis kit
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
256 Hiscript Ii 1st Strand Cdna Synthesis Kit, supplied by Vazyme Biotech Co, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/HiScript+III+1st+Strand+cDNA+Synthesis+Kit+%2BgDNA+wiper/ppr0766129-124-1-9
Average 99 stars, based on 1 article reviews
256 hiscript ii 1st strand cdna synthesis kit - by Bioz Stars, 2026-11
99/100 stars
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256-pixel silicon diode array  (Hamamatsu)
90
Hamamatsu 256-pixel silicon diode array
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
256 Pixel Silicon Diode Array, supplied by Hamamatsu, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/256+pixel+silicon+diode+array/10__1039_slash_c8fd00201k-235-7-12
Average 90 stars, based on 1 article reviews
256-pixel silicon diode array - by Bioz Stars, 2026-11
90/100 stars
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jasco 6200 ft ir spectrometer  (JASCO Inc)
99
JASCO Inc jasco 6200 ft ir spectrometer
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
Jasco 6200 Ft Ir Spectrometer, supplied by JASCO Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/JASCO+Probe+Raman+Spectrometer/10__1016_slash_j__molstruc__2024__140094-70-12-12
Average 99 stars, based on 1 article reviews
jasco 6200 ft ir spectrometer - by Bioz Stars, 2026-11
99/100 stars
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vevolazr; lz550  (FUJIFILM)
90
FUJIFILM vevolazr; lz550
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
Vevolazr; Lz550, supplied by FUJIFILM, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/mx550d+transducer/pmc04948629-56-14-20
Average 90 stars, based on 1 article reviews
vevolazr; lz550 - by Bioz Stars, 2026-11
90/100 stars
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iscript cdna synthesis 256 kit  (Bio-Rad)
99
Bio-Rad iscript cdna synthesis 256 kit
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
Iscript Cdna Synthesis 256 Kit, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/IScript+C+DNA+Synthesis+Kit/10__1158_slash_0008___5472__can___25___0766-117-18-24
Average 99 stars, based on 1 article reviews
iscript cdna synthesis 256 kit - by Bioz Stars, 2026-11
99/100 stars
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concentric microdialysis probes (2 mm membrane length cut off 6000 da; cma-11  (CMA Microdialysis)
90
CMA Microdialysis concentric microdialysis probes (2 mm membrane length cut off 6000 da; cma-11
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
Concentric Microdialysis Probes (2 Mm Membrane Length Cut Off 6000 Da; Cma 11, supplied by CMA Microdialysis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/cma+600+analyzer/10__1523_slash_jneurosci__1931___17__2018-116-32-45
Average 90 stars, based on 1 article reviews
concentric microdialysis probes (2 mm membrane length cut off 6000 da; cma-11 - by Bioz Stars, 2026-11
90/100 stars
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highresolution ultrasound probe  (Siemens AG)
90
Siemens AG highresolution ultrasound probe
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
Highresolution Ultrasound Probe, supplied by Siemens AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/highresolution+ultrasound+probe/pm17711544-51-28-41
Average 90 stars, based on 1 article reviews
highresolution ultrasound probe - by Bioz Stars, 2026-11
90/100 stars
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antifoxo1 phospho ser256  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc antifoxo1 phospho ser256
A. Schematic representation of the experimental design. Briefly, we used functional <t>Ultrasound</t> (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.
Antifoxo1 Phospho Ser256, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/2%2E56+real+mastermix+probe/Phospho-FoxO1+(Ser256)+Antibody/pm16679294-274-11-13
Average 96 stars, based on 1 article reviews
antifoxo1 phospho ser256 - by Bioz Stars, 2026-11
96/100 stars
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A. Schematic representation of the experimental design. Briefly, we used functional Ultrasound (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.

Journal: bioRxiv

Article Title: Dual-action nanoconjugate for overcoming r-tPA-resistant clots

doi: 10.64898/2026.05.13.725039

Figure Lengend Snippet: A. Schematic representation of the experimental design. Briefly, we used functional Ultrasound (fUS) imaging to quantify reperfusion in the ischemic area. Before inducing the IS, a 5-min acquisition was performed to have the baseline (T0) cerebral blood volume (CBV) of the mice. Then IS was induced by applying AlCl 3 on the MCA for 5 minutes. 15 minutes after, a 45-minute acquisition began to follow any changes in the CBV in the ischemic area. 5 minutes after the beginning of the 45-minutes acquisition, one of the treatments: IO@PDA (2mg/kg); DNase (1.37 mg/kg); tPA (10 mg/kg); a combination of IO@PDA (2 mg/kg) + tPA (2.5 mg/kg) + DNase (1.37 mg/kg) and the IO@PDA@tPA@DNase conjugate (corresponding to 2.5 mg/kg tPA and 1.37 mg/kg DNase equivalency) was administered to the mice (corresponding to 20 minutes post ischemic events). B. CBV variation of the ipsilateral isocortex of IO@PDA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). C. CBV variation of the ipsilateral isocortex DNase-treated mice (percentage from baseline (T0), n=6, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). D. CBV variation of the ipsilateral isocortex tPA-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). E. CBV variation of the ipsilateral isocortex IO@PDA + tPA + DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). F. CBV variation of the ipsilateral isocortex IO@PDA@tPA@DNase-treated mice (percentage from baseline (T0), n=5, 2-way ANOVA, Multiple comparisons (T0 vs Tn+1), **** p < 0.0001). G. Representative images obtained during baseline (T0); 20 minutes and 60 minutes post IS for IO@PDA@tPA@DNase-treated mice.

Article Snippet: All ultrasound imaging acquisitions were performed from bregma -3 mm to bregma +1 mm, both before and 15 minutes after stroke onset, using an ultrafast scanner (Iconeus One, Iconeus, France), the IcoScan acquisition software, and a dedicated ultrasound probe (Iconeus IcoPrime-4D MultiArray, 15 MHz, 256 elements, 100 μm pitch).

Techniques: Functional Assay, Imaging